Cholera Bacteriophages Revisited
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منابع مشابه
Vibriophage and Cholera Disease
Phage typing is an important tool to discriminate the strains of Vibrio cholerae from epidemiological point of view. National Institute of Cholera & Enteric Diseases is engaged in research on cholera phages since decades in India. Bacteriophages have long been used for classification and discrimination of bacterial strains. Cholera, an endemic disease in Indian subcontinent with mild to lethal ...
متن کاملEvidence of a Dominant Lineage of Vibrio cholerae-Specific Lytic Bacteriophages Shed by Cholera Patients over a 10-Year Period in Dhaka, Bangladesh
Lytic bacteriophages are hypothesized to contribute to the seasonality and duration of cholera epidemics in Bangladesh. However, the bacteriophages contributing to this phenomenon have yet to be characterized at a molecular genetic level. In this study, we isolated and sequenced the genomes of 15 bacteriophages from stool samples from cholera patients spanning a 10-year surveillance period in D...
متن کاملRepair of ultraviolet light-induced DNA damage in cholera bacteriophages.
DNA repair-proficient and -deficient strains of Vibrio cholerae were used to examine host cell reactivation, Weigle reactivation and photoreactivation of u.v.-irradiated cholera bacteriophages. U.v. light-induced DNA damage in phages of different morphological and serological groups could be efficiently photoreactivated. Host cell reactivation of irradiated phages of different groups was differ...
متن کاملA cocktail of three virulent bacteriophages prevents Vibrio cholerae infection in animal models
Effective prevention strategies will be essential in reducing disease burden due to bacterial infections. Here we harness the specificity and rapid-acting properties of bacteriophages as a potential prophylaxis therapy for cholera, a severely dehydrating disease caused by Vibrio cholerae. To this end, we test a cocktail of three virulent phages in two animal models of cholera pathogenesis (infa...
متن کاملComplete Genome Sequences of Vibrio cholerae-Specific Bacteriophages 24 and X29
The complete genomes of two Vibrio cholerae bacteriophages of potential interest for cholera bacteriophage (phage) therapy were sequenced and annotated. The genome size of phage 24 is 44,395 bp encoding 71 putative proteins, and that of phage X29 is 41,569 bp encoding 68 putative proteins.
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